Publications

Peer-​​reviewed Publications.

  • 1

    Bell AW, et al. A HUPO test sam­ple study reveals com­mon pro­blems in mass spectrometry-​​based pro­teo­mics. Nat Methods. 2009.
  • 2

    Chen XF, Zhou LX, Liu YD, Ping P , Chen YH, Cao M, Sun J. [Com­pa­ra­tive analy­sis of three dif­fe­rent sur­gi­cal approaches to vari­co­ce­lec­tomy]. Zhonghua Nan Ke Xue. 2009;15:413 – 6.
  • 3

    Gomes AV, Young GW, Wang Y, Zong C, Egh­bali M, Drews O, Lu H, Ste­fani E, Ping P . Con­tras­ting pro­teome bio­logy and func­tio­nal hete­ro­ge­neity of the 20 S pro­tea­some com­ple­xes in mam­ma­lian tis­sues. Mol Cell Pro­teo­mics. 2009;8:302 – 15.
  • 4

    Lu G, Sun H, She P, Youn JY, War­bur­ton S, Ping P , Von­driska TM, Cai H, Lynch CJ, Wang Y. Pro­tein phospha­tase 2Cm is a cri­ti­cal regu­la­tor of branched-​​chain amino acid cata­bo­lism in mice and cul­tu­red cells. J Clin Invest. 2009;119:1678 – 87.
  • 5

    Mayr M, Liem D, Zhang J, Li X, Avli­ya­ku­lov NK, Yang JI, Young G, Von­driska TM, Ladroue C, Madhu B, Grif­fiths JR, Gomes A, Xu Q, Ping P . Pro­teo­mic and meta­bo­lo­mic analy­sis of car­dio­pro­tec­tion: Inter­play bet­ween pro­tein kinase C epsi­lon and delta in regu­la­ting glu­cose meta­bo­lism of murine hearts. J Mol Cell Car­diol. 2009;46:268 – 77.
  • 6

    Ping P . Get­ting to the heart of pro­teo­mics. N Engl J Med. 2009;360:532 – 4.
  • 7

    Rodri­guez H, Sny­der M, Uhlen M, Andrews P, Bea­vis R, Borchers C, Chal­kley RJ, Cho SY, Cot­tingham K, Dunn M, Dylag T, Edgar R, Hare P, Heck AJ, Hirsch RF, Ken­nedy K, Kolar P, Kraus HJ, Mallick P, Nes­vizhs­kii A, Ping P , Pon­ten F, Yang L, Yates JR, Stein SE, Herm­ja­kob H, Kin­sin­ger CR, Apwei­ler R. Recom­men­da­tions from the 2008 Inter­na­tio­nal Sum­mit on Pro­teo­mics Data Release and Sha­ring Policy: the Ams­ter­dam prin­ci­ples. J Pro­teome Res. 2009;8:3689 – 92.
  • 8

    Ujwal R, Cas­cio D, Chap­tal V, Ping P , Abram­son J. Crys­tal pac­king analy­sis of murine VDAC1 crys­tals in a lipi­dic envi­ron­ment reveals novel insights on oli­go­me­ri­za­tion and orien­ta­tion. Chan­nels (Aus­tin). 2009;3:167 – 70.
  • 9

    Wu HY, Tseng VS, Chen LC, Chang YC, Ping P , Liao CC, Tsay YG, Yu JS, Liao PC. Com­bi­ning alka­line phospha­tase treat­ment and hybrid linear ion trap/​Orbitrap high mass accu­racy liquid chromatography-​​mass spec­tro­metry data for the effi­cient and con­fi­dent iden­ti­fi­ca­tion of pro­tein phosphory­la­tion. Anal Chem. 2009;81:7778 – 87.
  • 10

    Lu H, Zong C, Wang Y, Young GW, Deng N, Souda P, Li X, Whi­te­legge J, Drews O, Yang PY, Ping P . Revea­ling the dyna­mics of 20S pro­tea­some phospho­pro­teome: a com­bi­ned CID and ETD approach. Mol Cell Pro­teo­mics. 2008 Jun 25. [Epub ahead of print]
  • 11

    Zhang J, Liem DA, Mue­ller M, Wang Y, Zong C, Deng N, Von­driska TM, Korge P, Drews O, Mac­le­llan WR, Honda H, Weiss JN, Apwei­ler R, Ping P . Alte­red pro­teome bio­logy of car­diac mitochon­dria under stress con­di­tions. J Pro­teome Res. 2008;7:2204 – 14.

  • 12

    Ping P , Ber­ge­ron J, Apwei­ler R. Wiley-​​VCH and HUPO: a glo­bal effort to advance pro­teo­mic science. Pro­teo­mics. 2008;8:4 – 6.

  • 13

    War­bur­ton S, White MY, Van Eyk JE, Cot­ter RJ, Ping P , Dunn MJ, Von­driska TM. Car­dio­vas­cu­lar Ini­tia­tive of the Human Pro­teome Orga­ni­sa­tion, 5 th Workshop Octo­ber 2007, Seoul, Korea. Pro­teo­mics. 2008;8:924 – 6.

  • 14

    Baldán A, Gomes AV, Ping P , Edwards PA. Loss of ABCG1 results in chro­nic pul­mo­nary inflam­ma­tion. J Immu­nol. 2008;180:3560 – 8.

  • 15

    Zhang J, Li X, Mue­ller M, Wang Y, Zong C, Deng N, Von­driska TM, Liem DA, Yang JI, Korge P, Honda H, Weiss JN, Apwei­ler R, Ping P . Sys­te­ma­tic cha­rac­te­ri­za­tion of the murine mitochon­drial pro­teome using func­tio­nally vali­da­ted car­diac mitochon­dria. Pro­teo­mics. 2008;8:1564 – 75.
  • 16

    Young GW, Wang Y, Ping P . Unders­tan­ding pro­tea­some assembly and regu­la­tion: impor­tance to car­dio­vas­cu­lar medi­cine. Trends Car­dio­vasc Med. 2008;18:93 – 8.

  • 17

    Zong C, Young GW, Wang Y, Lu H, Deng N, Drews O, Ping P . Two-​​dimensional electrophoresis-​​based cha­rac­te­ri­za­tion of post-​​translational modi­fi­ca­tions of mam­ma­lian 20S pro­tea­some com­ple­xes. Pro­teo­mics. 2008;8:5025 – 37.
  • 18

    Orchard S, Ping P . HUPO World Con­gress Publi­ca­tion Com­mit­tee mee­ting. August 2008, Ams­ter­dam, The Nether­lands. Pro­teo­mics. 2009;9:502 – 3.
  • 19

    Zhang J, Liem DA, Mue­ller M, Wang Y, Zong C, Deng N, Von­driska TM, Korge P, Drews O, Mac­le­llan WR, Honda H, Weiss JN, Apwei­ler R, Ping P . Alte­red pro­teome bio­logy of car­diac mitochon­dria under stress con­di­tions. J Pro­teome Res. 2008;7:2204 – 14.
  • 20

    Ye WJ, Ping P , Liu YD, Li Z, Huang YR. Sin­gle stage dor­sal inlay buc­cal muco­sal graft with tubu­la­ri­zed inci­sed ureth­ral plate tech­ni­que for hypos­pa­dias reo­pe­ra­tions. Asian J Androl. 2008;10:682 – 6.
  • 21

    Lu H, Zong C, Wang Y, Young GW, Deng N, Souda P, Li X, Whi­te­legge J, Drews O, Yang PY, Ping P . Revea­ling the dyna­mics of the 20 S pro­tea­some phospho­pro­teome: a com­bi­ned CID and elec­tron trans­fer dis­so­cia­tion approach. Mol Cell Pro­teo­mics. 2008;7:2073 – 89.
  • 22

    Liem DA, Zhao P, Ange­lis E, Chan SS, Zhang J, Wang G, Berthet C, Kal­dis P, Ping P , Mac­Le­llan WR. Cyclin-​​dependent kinase 2 sig­na­ling regu­la­tes myo­car­dial ischemia/​reperfusion injury. J Mol Cell Car­diol. 2008;45:610 – 6.
  • 23

    Korge P, Ping P , Weiss JN. Reac­tive oxy­gen spe­cies pro­duc­tion in ener­gi­zed car­diac mitochon­dria during hypoxia/​reoxygenation: modu­la­tion by nitric oxide. Circ Res. 2008;103:873 – 80.
  • 24

    Jiang H, Shang XJ, Guo J, Li Z, Zhao LM, Shao Y, Ping P , Huang YF, Zhu JC. [Multi-​​centered cli­ni­cal trial of Fufang Xuanju cap­sule for oli­goasthe­nos­per­mia]. Zhonghua Nan Ke Xue. 2008;14:755 – 8.
  • 25

    Chen R, Fu MG, Lu Y, Wang L, Ping P , Fan ZH. [Effects of anti­sense oli­go­nuc­leo­ti­des on the expres­sion of focal adhe­sion kinase gene and colla­gen sythe­sis in the cul­tu­red human fibro­blasts of hyper­trophic scar]. Zhonghua Zheng Xing Wai Ke Za Zhi. 2008;24:475 – 7.
  • 26

    Drake TA, Ping P . The­ma­tic review series: sys­tems bio­logy approaches to meta­bo­lic and car­dio­vas­cu­lar disor­ders. Pro­teo­mics approaches to the sys­tems bio­logy of car­dio­vas­cu­lar disea­ses. J Lipid Res. 2007;48:1 – 8.
  • 27

    Kawa­guchi R, Yu J, Honda J, Hu J, Whi­te­legge J, Ping P , Wiita P, Bok D, Sun H. A mem­brane recep­tor for reti­nol bin­ding pro­tein media­tes cellu­lar uptake of vita­min A. Science. 2007;315:820 – 5.

  • 28

    Orchard S, Heck A, Uhlen M, Ping P . Publi­ca­tion Com­mit­tee mee­ting. HUPO 5 th annual World Con­gress. Long Beach, CA, USA 30 Octo­ber 2006 . Pro­teo­mics. 2007;7:1009 – 11.
  • 29

    Drews O, Zong C, Ping P . Explo­ring pro­tea­some com­ple­xes by pro­teo­mic approaches. Pro­teo­mics. 2007;7:1047 – 58.
  • 30

    Drews O, Wild­gru­ber R, Zong C, Sukop U, Nis­sum M, Weber G, Gomes AV, Ping P . Mam­ma­lian pro­tea­some sub­po­pu­la­tions with dis­tinct mole­cu­lar com­po­si­tions and pro­teoly­tic acti­vi­ties. Mol Cell Pro­teo­mics. 2007;6:2021 – 31.

  • 31

    Liem DA, Honda HM, Zhang J, Woo D, Ping P . Past and pre­sent course of car­dio­pro­tec­tion against ischemia-​​reperfusion injury. J Appl Phy­siol. 2007;103:2129 – 36.
  • 32

    Tay­lor CF, Paton NW, Lilley KS, Binz PA, Julian RK Jr, Jones AR, Zhu W, Apwei­ler R, Aeber­sold R, Deutsch EW, Dunn MJ, Heck AJ, Leit­ner A, Macht M, Mann M, Mar­tens L, Neu­bert TA, Pat­ter­son SD, Ping P , Sey­mour SL, Souda P, Tsu­gita A, Van­de­kerckhove J, Von­driska TM, Whi­te­legge JP, Wil­kins MR, Xena­rios I, Yates JR 3 rd, Herm­ja­kob H. The mini­mum infor­ma­tion about a pro­teo­mics expe­ri­ment (MIAPE). Nat Bio­tech­nol. 2007;25:887 – 93.
  • 33

    Hai-​​Long H, Jian Z, Ping-​​Ping Y, Liang C, Xun L, Shan ZZ, Yan-​​Sheng Y. Gene­tic cha­rac­te­ri­za­tion of CRF01_​AE full-​​length human immu­no­de­fi­ciency virus type 1 sequen­ces from Fujian, China. AIDS Res Hum Retro­vi­ru­ses. 2007;23:569 – 74.
  • 34

    Chun-​​mao H, Su-​​yi W, Ping-​​ping L, Hang-​​hui C. Human bone marrow-​​derived mesenchy­mal stem cells dif­fe­ren­tiate into epidermal-​​like cells in vitro. Dif­fe­ren­tia­tion. 2007;75:292 – 8.
  • 35

    Abde­lla­tif AA, Pelt JL, Ben­ton RL, Howard RM, Tsoul­fas P, Ping P , Xu XM, Whit­te­more SR. Gene deli­very to the spi­nal cord: com­pa­ri­son bet­ween len­ti­vi­ral, ade­no­vi­ral, and retro­vi­ral vec­tor deli­very sys­tems. J Neu­rosci Res. 2006;84:553 – 67.
  • 36

    Zong C, Gomes AV, Drews O, Li X, Young GW, Berhane B, Qiao X, French SW, Bardag-​​Gorce F, Ping P . Regu­la­tion of murine car­diac 20S pro­tea­so­mes: role of asso­cia­ting part­ners. Circ Res. 2006;99:372 – 80.
  • 37

    Orchard S, Ping P . HUPO Publi­ca­tions Com­mit­tee Mee­ting: 21 April 2006, San Fran­cisco, CA, USA . Pro­teo­mics. 2006;6:4436 – 8.
  • 38

    Mayr M, Zhang J, Greene AS, Gut­ter­man D, Per­loff J, Ping P . Pro­teo­mic based deve­lop­ment of bio­mar­kers in car­dio­vas­cu­lar disease: mecha­nis­tic, cli­ni­cal, and the­ra­peu­tic insights. Mol Cell Pro­teo­mics. 2006;5:1853 – 1864.
  • 39

    Gomes AV, Zong C, Ping P . Pro­tein degra­da­tion by the 26S pro­tea­some sys­tem in the nor­mal and stres­sed myo­car­dium. Antio­xid Redox Sig­nal. 2006;8:1677 – 91.
  • 40

    Gomes AV, Zong C, Edmond­son RD, Li X, Ste­fani E, Zhang J, Jones RC, Thy­pa­ram­bil S, Wang GW, Qiao X, Bardag-​​Gorce F, Ping P . Map­ping the murine car­diac 26S pro­tea­some com­ple­xes. Circ Res. 2006;99:362 – 71.
  • 41

    Arab S, Gra­mo­lini AO, Ping P , Kis­lin­ger T, Stan­ley B, van Eyk J, Ouzou­nian M, Mac­Len­nan DH, Emili A, Liu PP. Car­dio­vas­cu­lar pro­teo­mics: tools to deve­lop novel bio­mar­kers and poten­tial appli­ca­tions. J Am Coll Car­diol. 2006;48:1733 – 41.

  • 42

    Honda HM, Ping P . Mitochon­drial per­mea­bi­lity tran­si­tion in car­diac cell injury and death. Car­dio­vasc Drugs Ther. 2006;20:425 – 32.
  • 43

    Li Q, Ping P , Jiang H, Liu K. Nerve con­duit filled with GDNF gene-​​modified Sch­wann cells enhan­ces rege­ne­ra­tion of the periphe­ral nerve. Mic­ro­sur­gery. 2006;26:116 – 21.
  • 44

    Zhang J, Bai­nes CP, Zong C, Card­well EM, Wang G, Von­driska TM, Ping P . Func­tio­nal pro­teo­mic analy­sis of a three-​​tier PKCepsilon-​​Akt-​​eNOS sig­na­ling module in car­diac pro­tec­tion. Am J Phy­siol Heart Circ Phy­siol. 2005;288:H954-61 .

  • 45

    Wang G, Liem DA, Von­driska TM, Honda HM, Korge P, Pan­ta­leon DM, Qiao X, Wang Y, Weiss JN, Ping P . Nitric oxide donors pro­tect murine myo­car­dium against infarc­tion via modu­la­tion of mitochon­drial per­mea­bi­lity tran­si­tion. Am J Phy­siol Heart Circ Phy­siol. 2005;288:H1290-5 .
  • 46

    Ping P , Von­driska TM, Creigh­ton CJ, Gandhi TK, Yang Z, Menon R, Kwon, MS, Cho SY, Drwal G, Kell­mann M, Peri S, Suresh S, Gron­borg M, Molina H, Chaer­kady R, Rekha B, Shet AS, Gersz­ten RE, Wu H, Raf­tery M, Wasin­ger V, Schulz-​​Knappe P, Hanash SM, Paik YK, Han­cock WS, Sta­tes DJ, Omenn GS, Pan­dey A. A func­tio­nal anno­ta­tion of sub­pro­teo­mes in human plasma. Pro­teo­mics. 2005;5:3506 – 19.
  • 47

    Omenn GS, Sta­tes DJ, Adamski M, Black­well TW, Menon R, Herm­ja­kob H, Apwei­ler R, Haab BB, Simp­son RJ, Eddes JA, Kapp EA, Moritz RL, Chan DW, Rai AJ, Admon A, Aeber­sold R, Eng J, Han­cock WS, Hefta SA, Meyer H, Paik YK, Yoo JS, Ping P , Pounds J, Adkins J, Qian X, Wang R, Wasin­ger V, Wu CY, Zhao X, Zeng R, Archa­kov A, Tsu­gita A, Beer I, Pan­dey A, Pisano M, Andrews P, Tam­men H, Speicher DW, Hanash SM. Over­view of the HUPO Plasma Pro­teome Pro­ject: results from the pilot phase with 35 colla­bo­ra­ting labo­ra­to­ries and mul­ti­ple analy­ti­cal groups, gene­ra­ting a core data­set of 3020 pro­teins and a publicly-​​available data­base. Pro­teo­mics. 2005;5:3226 – 45.
  • 48

    Omenn GS, Ping P . HUPO 3 rd annual World Con­gress on Pro­teo­mics. 25-​​27 th Octo­ber, 2004, Bei­jing, China. Expert Rev Pro­teo­mics. 2005;2:9 – 12.
  • 49

    McCarthy J, McLeod CJ, Min­ners J, Essop MF, Ping P , Sack MN. PKCep­si­lon acti­va­tion aug­ments car­diac mitochon­drial res­pi­ra­tory post-​​anoxic reserve – a puta­tive mecha­nism in PKCep­si­lon car­dio­pro­tec­tion. J Mol Cell Car­diol. 2005;38:697 – 700.
  • 50

    Gomes AV, Zong C, Edmond­son RD, Berhane BT, Wang GW, Le S, Young G, Zhang J, Von­driska TM, Whi­te­legge JP, Jones RC, Joshua IG, Thy­pa­ram­bil S, Pan­ta­leon, D, Qiao J, Loo J, Ping P . The murine car­diac 26S pro­tea­some: an orga­ne­lle awai­ting explo­ra­tion. Ann N Y Acad Sci. 2005;1047:197 – 207.
  • 51

    Cao Q, Xu XM, Dev­ries WH, Enz­mann GU, Ping P , Tsoul­fas P, Wood PM, Bunge MB, Whit­te­more SR. Func­tio­nal reco­very in trau­ma­tic spi­nal cord injury after trans­plan­ta­tion of multineurotrophin-​​expressing glial-​​restricted pre­cur­sor cells. J Neu­rosci. 2005;25:6947 – 57.
  • 52

    Berhane BT, Zong C, Liem DA, Huang A, Le S, Edmond­son RD, Jones RC, Qiao X, Whi­te­legge JP, Ping P , Von­driska TM. Cardiovascular-​​related pro­teins iden­ti­fied in human plasma by the HUPO Plasma Pro­teome Pro­ject pilot phase. Pro­teo­mics. 2005;5:3520 – 30.
  • 53

    Liem DA , Wang GW, Von­driska TM, Honda HM, Qiao X, Korge P, Pan­ta­leon DM, Wang Y, Weiss JN, Ping P . Nitric oxide indu­ces late phase pre­con­di­tio­ning against myo­car­dial infarc­tion via modu­la­tion of mitochon­drial per­mea­bi­lity tran­si­tion. Am J Phy­siol. 2005;288:H1290-5

  • 54

    Ping P , Wang W, Chen X, Jing X. Poly(epsilon-caprolactone) pol­yu­rethane and its shape-​​memory pro­perty. Bio­mac­ro­mo­le­cu­les. 2005;6:587 – 92.
  • 55

    Doble BW, Dang X, Ping P , Fan­drich RR, Nic­kel BE, Jin Y, Cat­tini PA, Kar­dami E. Phosphory­la­tion of serine 262 in the gap junc­tion pro­tein connexin-​​43 regu­la­tes DNA synthe­sis in cell-​​cell con­tact for­ming car­diom­yocy­tes. J Cell Sci. 2004;117:507 – 14.
  • 56

    Zhang J, Ping P , Wang GW, Lu M, Pan­ta­leon D, Tang XL, Bolli R, Von­driska TM. Bmx, a mem­ber of the Tec family of non­re­cep­tor tyro­sine kina­ses, is a novel par­ti­ci­pant in phar­ma­co­lo­gi­cal car­dio­pro­tec­tion. Am J Phy­siol Heart Circ Phy­siol. 2004;287:H2364-6 .
  • 57

    Von­driska TM, Pass JM, Ping P . Scaf­fold pro­teins and assembly of mul­ti­pro­tein sig­na­ling com­ple­xes. J Mol Cell Car­diol. 2004;37:391 – 7.
  • 58

    Mac­Le­llan WR, Ping P , Von­driska T. Heart disease lea­ves its mark: proteomics-​​based bio­sig­na­tu­res in acute coro­nary syn­dro­mes. J Am Coll Car­diol. 2004;44:1584 – 6.
  • 59

    Ping P . Iden­ti­fi­ca­tion of novel sig­na­ling com­ple­xes by func­tio­nal pro­teo­mics. Circ Res. 2003 Oct 3;93(7):595 – 603.
  • 60

    Von­driska TM, Ping P . Mul­ti­pro­tein sig­na­ling com­ple­xes and regu­la­tion of car­diac phe­notype. J Mol Cell Car­diol. 2003 Sep;35:1027 – 33.
  • 61

    Tang XL, Kodani E, Takano H, Hill M, Shin­mura K, Von­driska TM, Ping P , Bolli R. Pro­tein tyro­sine kinase sig­na­ling is neces­sary for NO donor-​​induced late pre­con­di­tio­ning against myo­car­dial stun­ning. Am J Phy­siol Heart Circ Phy­siol. 2003;284:H1441-8 .

  • 62

    Bai­nes CP, Song CX, Zheng YT, Wang GW, Zhang J, Wang OL, Guo Y, Bolli R, Card­well EM, Ping P . Pro­tein kinase Cep­si­lon inte­racts with and inhi­bits the per­mea­bi­lity tran­si­tion pore in car­diac mitochon­dria. Circ Res. 2003;92:873 – 80.
  • 63

    Prabhu SD, Wang G, Luo J, Gu Y, Ping P , Chan­dra­se­kar B. Beta-​​adrenergic recep­tor bloc­kade modu­la­tes Bcl-X(S) expres­sion and redu­ces apop­to­sis in fai­ling myo­car­dium. J Mol Cell Car­diol. 2003;35:483 – 93.
  • 64

    Ping P . A new chap­ter in car­diac PKC sig­na­ling stu­dies: searching for isoform-​​specific mole­cu­lar tar­gets. Focus on: “isoenzyme-​​selective regu­la­tion of SERCA2 gene expres­sion by pro­tein kinase C in neo­na­tal rat ven­tri­cu­lar myocy­tes”. Am J Phy­siol Cell Phy­siol. 2003;285:C19-21 .
  • 65

    Zhang J, Ping P , Von­driska TM, Tang XL, Wang GW, Card­well EM, Bolli R. Car­dio­pro­tec­tion invol­ves acti­va­tion of NF-​​kappa B via PKC-​​dependent tyro­sine and serine phosphory­la­tion of I kappa B-​​alpha. Am J Phy­siol Heart Circ Phy­siol. 2003;285:H1753-8 .
  • 66

    Pass JM, Zhang J, Von­driska TM, Ping P . Func­tio­nal pro­teo­mic analy­sis of the pro­tein kinase C sig­na­ling sys­tem. Methods Mol Biol. 2003;233:369 – 85.

  • 67

    Weiss JN, Korge P, Honda HM, Ping P . Role of the mitochon­drial per­mea­bi­lity tran­si­tion in myo­car­dial disease. Circ Res. 2003;93:292 – 301.
  • 68

    Ping P , Bai­nes CP, Gu Y, Prabhu SD, Zhang J, Tsai LL, Card­well E, Zong NC, Von­driska TM, Korge P, Bhat­na­gar A, Wang GW. Car­diac toxic effects of trans-​​2-​​hexenal are media­ted by induc­tion of car­diom­yocyte apop­to­tic path­ways. Car­dio­vasc Toxi­col. 2003;3:341 – 51.
  • 69

    Ping P , Li QF, Zhang DS. [An expe­ri­ment study on repair of periphe­ral nerve defects by GDNF gene modi­fied Sch­wann cells]. Zhonghua Zheng Xing Wai Ke Za Zhi. 2003;19:369 – 72.
  • 70

    Song C, Von­driska TM, Wang GW, Klein JB, Cao X, Zhang J, Kang YJ, D’Souza S, Ping P . Mole­cu­lar con­for­ma­tion dic­ta­tes sig­na­ling module for­ma­tion: exam­ple of PKCe and Src tyro­sine kinase. Am J Phy­siol Heart Circ Phy­siol. 2002;282:H1166-71 .
  • 71

    Bala­fa­nova Z, Bolli R, Zhang J, Zheng Y, Pass JM, Bhat­na­gar A, Tang XL, Wang O, Card­well E, Ping P . Nitric oxide (NO) indu­ces nitra­tion of pro­tein kinase C epsi­lon (PKCe), faci­li­ta­ting PKCe enhan­ced PKCe-​​RACK2 inte­rac­tions: a novel mecha­nism of no-​​triggered acti­va­tion of PKCe. J Biol Chem. 2002;277:15021 – 15027.
  • 72

    Ping P , Song C, Zhang J, Guo Y, Cao X, Li RC, Wu W, Von­driska TM, Pass JM, Tang XL, Pierce WM, Bolli R. For­ma­tion of pro­tein kinase Ce-​​Lck sig­na­ling modu­les con­fers car­dio­pro­tec­tion. J Clin Invest. 2002;109:499 – 507.
  • 73

    Bai­nes CP, Zhang J, Wang GW, Zheng YT, Xiu JX, Card­well EM, Bolli R, Ping P . Mitochon­drial PKCe and MAPK form sig­na­ling modu­les in the murine heart: enhan­ced mitochon­drial PKCe-​​MAPK inte­rac­tions and dif­fe­ren­tial MAPK acti­va­tion in PKCe-​​induced car­dio­pro­tec­tion. Circ Res. 2002;90:390 – 7.
  • 74

    Cross HR, Murphy E, Bolli R, Ping P , Steen­ber­gen C. Expres­sion of acti­va­ted PKC epsi­lon (PKCe) pro­tects the ische­mic heart, without atte­nua­ting ische­mic H(+) pro­duc­tion. J Mol Cell Car­diol. 2002;34:361 – 7.
  • 75

    Edmond­son RD, Von­driska TM, Bie­der­man KJ, Zhang J, Jones RC, Zheng Y, Allen DL, Xiu JX, Card­well EM, Pisano MR, Ping P . Pro­tein kinase C e sig­na­ling com­ple­xes inc­lude meta­bo­lism– and transcription/​translation-​​related pro­teins: com­pli­men­tary sepa­ra­tion tech­ni­ques with LC/​MS/​MS. Mol Cell Pro­teo­mics. 2002;1:421 – 33.
  • 76

    Von­driska TM, Ping P . Func­tio­nal pro­teo­mics to study pro­tec­tion of the ischae­mic myo­car­dium. Expert Opin Ther Tar­gets. 2002;6:563 – 70.

  • 77

    Li Q, Ping P , Zhang D. [Vas­cu­lar endothe­lial growth fac­tor (VEGF) acce­le­ra­tes matu­ra­tion of pre­fa­bri­ca­ted flap]. Zhonghua Zheng Xing Wai Ke Za Zhi. 2002;18:69 – 71.
  • 78

    Wang JF, Yang Y, Wang G, Min J, Sulli­van MF, Ping P , Xiao YF, Mor­gan JP. Embr­yo­nic stem cells atte­nuate viral myo­car­di­tis in murine model. Cell Trans­plant. 2002;11:753 – 8.
  • 79

    Rane MJ, Coxon PY, Powell DW, Webs­ter R, Klein JB, Pierce W, Ping P , McLeish KR. p38 Kinase-​​dependent MAPKAPK-​​2 acti­va­tion func­tions as 3-​​phosphoinositide-​​dependent kinase-​​2 for Akt in human neu­trophils. J Biol Chem. 2001;276:3517 – 23.
  • 80

    Ping P , Zhang J, Pierce WM Jr, Bolli R. Func­tio­nal pro­teo­mic analy­sis of pro­tein kinase C epsi­lon sig­na­ling com­ple­xes in the nor­mal heart and during car­dio­pro­tec­tion. Circ Res. 2001;88:59 – 62.
  • 81

    Pass JM, Zheng Y, Wead WB, Zhang J, Li RC, Bolli R, Ping P . PKCep­si­lon acti­va­tion indu­ces dicho­to­mous car­diac phe­noty­pes and modu­la­tes PKCepsilon-​​RACK inte­rac­tions and RACK expres­sion. Am J Phy­siol Heart Circ Phy­siol. 2001;280:H946-55 .
  • 82

    Von­driska TM, Klein JB, Ping P . Use of func­tio­nal pro­teo­mics to inves­ti­gate PKC epsilon-​​mediated car­dio­pro­tec­tion: the sig­na­ling module hypothe­sis. Am J Phy­siol Heart Circ Phy­siol. 2001;280:H1434-41 .
  • 83

    Bai­nes CP, Pass JM, Ping P . Pro­tein kina­ses and kinase-​​modulated effec­tors in the late phase of ische­mic pre­con­di­tio­ning. Basic Res Car­diol. 2001;96:207 – 18.
  • 84

    Von­driska TM, Zhang J, Song C, Tang XL, Cao X, Bai­nes CP, Pass JM, Wang S, Bolli R, Ping P . Pro­tein kinase C epsilon-​​Src modu­les direct sig­nal trans­duc­tion in nitric oxide-​​induced car­dio­pro­tec­tion: com­plex for­ma­tion as a means for car­dio­pro­tec­tive sig­na­ling . Circ Res . 2001;88:1306 – 13.
  • 85

    Pass JM, Gao J, Jones WK, Wead WB, Wu X, Zhang J, Bai­nes CP, Bolli R, Zheng YT, Joshua IG, Ping P . Enhan­ced PKC beta II trans­lo­ca­tion and PKC beta II-​​RACK1 inte­rac­tions in PKC epsilon-​​induced heart fai­lure: a role for RACK1 . Am J Phy­siol Heart Circ Phy­siol . 2001;281:H2500-10 .
  • 86

    Doble BW, Ping P , Fan­drich RR, Cat­tini PA, Kar­dami E. Pro­tein kinase C-​​e media­tes phor­bol ester-​​induced phosphory­la­tion of connexin-​​43 . Cell Adhes Com­mun . 2001;8:253 – 6.
  • 87

    Doble BW, Ping P , Kar­dami E. The epsi­lon subtype of pro­tein kinase C is requi­red for car­diom­yocyte connexin-​​43 phosphory­la­tion . Circ Res . 2000;86:293 – 301.
  • 88

    Ping P , Murphy E. Role of p38 mitogen-​​activated pro­tein kina­ses in pre­con­di­tio­ning: a detri­men­tal fac­tor or a pro­tec­tive kinase ? Circ Res . 2000;86:921 – 2.
  • 89

    Takeishi Y, Ping P , Bolli R, Kirk­pa­trick DL, Hoit BD, Walsh RA. Trans­ge­nic ove­rex­pres­sion of cons­ti­tu­ti­vely active pro­tein kinase C epsi­lon cau­ses con­cen­tric car­diac hyper­trophy . Circ Res . 2000;86:1218 – 23.
  • 90

    Li RC, Ping P , Zhang J, Wead WB, Cao X, Gao J, Zheng Y, Huang S, Han J, Bolli R. PKCep­si­lon modu­la­tes NF-​​kappaB and AP-​​1 via mitogen-​​activated pro­tein kina­ses in adult rab­bit car­diom­yocy­tes . Am J Phy­siol Heart Circ Phy­siol . 2000;279:H1679-89 .
  • 91

    Ping P , Li QF, Gan JL. [Neu­ro­bio­lo­gi­cal effect of nerve rege­ne­ra­tion con­di­tio­ned fluid on moto­neu­ron]. Zhong­guo Xiu Fu Chong Jian Wai Ke Za Zhi. 2000;14:325 – 7.
  • 92

    Ping P , Takano H, Zhang J, Tang XL, Qiu Y, Li RC, Baner­jee S, Dawn B, Bala­fa­nova Z, Bolli R. Isoform-​​selective acti­va­tion of pro­tein kinase C by nitric oxide in the heart of cons­cious rab­bits: a sig­na­ling mecha­nism for both nitric oxide-​​induced and ischemia-​​induced pre­con­di­tio­ning . Circ Res . 1999;84:587 – 604.
  • 93

    Ping P , Zhang J, Cao X, Li RC, Kong D, Tang XL, Qiu Y, Manchi­ka­la­pudi S, Aucham­pach JA, Black RG, Bolli R. PKC-​​dependent acti­va­tion of p44/​p42 MAPKs during myo­car­dial ischemia-​​reperfusion in cons­cious rab­bits . Am J Phy­siol . 1999;276:H1468-81 .
  • 94

    Ping P , Zhang J, Zheng YT, Li RC, Dawn B, Tang XL, Takano H, Bala­fa­nova Z, Bolli R. Demons­tra­tion of selec­tive pro­tein kinase C-​​dependent acti­va­tion of Src and Lck tyro­sine kina­ses during ische­mic pre­con­di­tio­ning in cons­cious rab­bits . Circ Res . 1999;85:542 – 50.
  • 95

    Ping P , Zhang J, Huang S, Cao X, Tang XL, Li RC, Zheng YT, Qiu Y, Clerk A, Sug­den P, Han J, Bolli R. PKC-​​dependent acti­va­tion of p46/​p54 JNKs during ische­mic pre­con­di­tio­ning in cons­cious rab­bits . Am J Phy­siol . 1999;277:H1771-85 .
  • 96

    Guo Y, Jones WK, Xuan YT, Tang XL, Bao W, Wu WJ, Han H, Lau­bach VE, Ping P , Yang Z, Qiu Y, Bolli R. The late phase of ische­mic pre­con­di­tio­ning is abro­ga­ted by tar­ge­ted dis­rup­tion of the indu­ci­ble NO synthase gene . Proc Natl Acad Sci U S A . 1999;96:11507 – 12.
  • 97

    Dawn B, Xuan YT, Qiu Y, Takano H, Tang XL, Ping P , Baner­jee S, Hill M, Bolli R. Bifunc­tio­nal role of pro­tein tyro­sine kina­ses in late pre­con­di­tio­ning against myo­car­dial stun­ning in cons­cious rab­bits . Circ Res . 1999;85:1154 – 63.
  • 98

    Ham­mond HK, Ping P , Insel PA. Car­diac G-​​protein recep­tor kinase acti­vity: effect of a beta-​​adrenergic recep­tor anta­go­nist . Adv Phar­ma­col . 1998;42:507 – 10.
  • 99

    Gao M, Ping P , Post S, Insel PA, Tang R, Ham­mond HK. Inc­rea­sed expres­sion of adenylylcyc­lase type VI pro­por­tio­na­tely inc­rea­ses beta-​​adrenergic receptor-​​stimulated pro­duc­tion of cAMP in neo­na­tal rat car­diac myocy­tes . Proc Natl Acad Sci U S A . 1998;95:1038 – 43.
  • 100

    Pal M, Toth A, Ping P , John­son PC. Capi­llary blood flow and tis­sue meta­bo­lism in ske­le­tal muscle during sym­pathe­tic trunk sti­mu­la­tion . Am J Phy­siol . 1998;274:H430-40 .
  • 101

    Qiu Y, Ping P , Tang XL, Manchi­ka­la­pudi S, Rizvi A, Zhang J, Takano H, Wu WJ, Tesch­ner S, Bolli R. Direct evi­dence that pro­tein kinase C plays an essen­tial role in the deve­lop­ment of late pre­con­di­tio­ning against myo­car­dial stun­ning in cons­cious rab­bits and that epsi­lon is the iso­form invol­ved . J Clin Invest . 1998;101:2182 – 98.
  • 102

    Bolli R, Dawn B, Tang XL, Qiu Y, Ping P , Xuan YT, Jones WK, Takano H, Guo Y, Zhang J. The nitric oxide hypothe­sis of late pre­con­di­tio­ning . Basic Res Car­diol . 1998;93:325 – 38.
  • 103

    Ping P , Anzai T, Gao M, Ham­mond HK. Adenylyl cyc­lase and G pro­tein recep­tor kinase expres­sion during deve­lop­ment of heart fai­lure . Am J Phy­siol . 1997;273:H707-17 .
  • 104

    Ping P , Zhang J, Qiu Y, Tang XL, Manchi­ka­la­pudi S, Cao X, Bolli R. Ische­mic pre­con­di­tio­ning indu­ces selec­tive trans­lo­ca­tion of pro­tein kinase C iso­forms epsi­lon and eta in the heart of cons­cious rab­bits without sub­ce­llu­lar redis­tri­bu­tion of total pro­tein kinase C acti­vity . Circ Res . 1997;81:404 – 14.
  • 105

    Gior­dano FJ, Ping P , McKir­nan MD, Nozaki S, DeMa­ria AN, Dill­mann WH, Mathieu-​​Costello O, Ham­mond HK. Intra­co­ro­nary gene trans­fer of fibro­blast growth factor-​​5 inc­rea­ses blood flow and con­trac­tile func­tion in an ische­mic region of the heart . Nat Med . 1996;2:534 – 9.
  • 106

    Ping P , Yang Q, Ham­mond HK. Alte­red beta-​​adrenergic recep­tor sig­na­ling in heart fai­lure, in vivo gene trans­fer via adeno and adeno-​​associated virus . Mic­ro­cir­cu­la­tion . 1996;3:225 – 8.
  • 107

    Ping P , Gelzer-​​Bell R, Roth DA, Kiel D, Insel PA, Ham­mond HK. Redu­ced beta-​​adrenergic recep­tor acti­va­tion dec­rea­ses G-​​protein expres­sion and beta-​​adrenergic recep­tor kinase acti­vity in por­cine heart . J Clin Invest . 1995;95:1271 – 80.
  • 108

    Ping P , John­son PC. Arte­rio­lar net­work res­ponse to pres­sure reduc­tion during sym­pathe­tic nerve sti­mu­la­tion in cat ske­le­tal muscle . Am J Phy­siol . 1994;266:H1251-9 .
  • 109

    Ping P , Ham­mond HK. Diverse G pro­tein and beta-​​adrenergic recep­tor mRNA expres­sion in nor­mal and fai­ling por­cine hearts . Am J Phy­siol . 1994;267:H2079-85 .
  • 110

    Ham­mond HK, Roth DA, McKir­nan MD, Ping P . Regio­nal myo­car­dial down­re­gu­la­tion of the inhi­bi­tory gua­no­sine triphosphate-​​binding pro­tein (Gi alpha 2) and beta-​​adrenergic recep­tors in a por­cine model of chro­nic epi­so­dic myo­car­dial ische­mia . J Clin Invest . 1993 Dec;92:2644 – 52.
  • 111

    Ping P , Faber JE. Cha­rac­te­ri­za­tion of alpha-​​adrenoceptor gene expres­sion in arte­rial and venous smooth muscle . Am J Phy­siol . 1993;265:H1501-9 .
  • 112

    Ping P , John­son PC. Mecha­nism of enhan­ced myo­ge­nic res­ponse in arte­rio­les during sym­pathe­tic nerve sti­mu­la­tion . Am J Phy­siol . 1992;263:H1185-9 .
  • 113

    Ping P , John­son PC. Role of myo­ge­nic res­ponse in enhan­cing auto­re­gu­la­tion of flow during sym­pathe­tic nerve sti­mu­la­tion . Am J Phy­siol . 1992;263:H1177-84 .