I am a second year graduate student from MCIP. I have a B.S. in Biochemistry and Molecular Biology from the University of California, Irvine. I am currently using a mass spectrometer based approach to study the proteasome and its associating proteins.
email: gwyoung@ucla.edu
Glen Young, BS
publications by Glen Young
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1
Mayr M, Liem D, Zhang J, Li X, Avliyakulov NK, Yang JI, Young G , Vondriska TM, Ladroue C, Madhu B, Griffiths JR, Gomes A, Xu Q, Ping P. Proteomic and metabolomic analysis of cardioprotection: Interplay between protein kinase C epsilon and delta in regulating glucose metabolism of murine hearts. J Mol Cell Cardiol. 2009;46:268 – 77.
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2
Gomes AV, Young GW , Wang Y, Zong C, Eghbali M, Drews O, Lu H, Stefani E, Ping P. Contrasting proteome biology and functional heterogeneity of the 20 S proteasome complexes in mammalian tissues. Mol Cell Proteomics. 2009;8:302 – 15.
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3
Lu H, Zong C, Wang Y, Young GW , Deng N, Souda P, Li X, Whitelegge J, Drews O, Yang PY, Ping P. Revealing the dynamics of 20S proteasome phosphoproteome: a combined CID and ETD approach. Mol Cell Proteomics. 2008 Jun 25. [Epub ahead of print]
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4
Young GW , Wang Y, Ping P. Understanding proteasome assembly and regulation: importance to cardiovascular medicine. Trends Cardiovasc Med. 2008;18:93 – 8.
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5
Zong C, Young GW , Wang Y, Lu H, Deng N, Drews O, Ping P. Two-dimensional electrophoresis-based characterization of post-translational modifications of mammalian 20S proteasome complexes. Proteomics. 2008;8:5025 – 37.
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6
Lu H, Zong C, Wang Y, Young GW , Deng N, Souda P, Li X, Whitelegge J, Drews O, Yang PY, Ping P. Revealing the dynamics of the 20 S proteasome phosphoproteome: a combined CID and electron transfer dissociation approach. Mol Cell Proteomics. 2008;7:2073 – 89.
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7
Zong C, Gomes AV, Drews O, Li X, Young GW , Berhane B, Qiao X, French SW, Bardag-Gorce F, Ping P. Regulation of murine cardiac 20S proteasomes: role of associating partners. Circ Res. 2006;99:372 – 80.
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8
Young GW , Hoofring SA, Mamula MJ, Doyle HA, Bunick GJ, Hu Y, Aswad DW. Protein L-isoaspartyl methyltransferase catalyzes in vivo racemization of Aspartate-25 in mammalian histone H2B . J Biol Chem. 2005 Jul 15;280(28):26094 – 8. Epub 2005 May 20
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9
Gomes AV, Zong C, Edmondson RD, Berhane BT, Wang GW, Le S, Young G , Zhang J, Vondriska TM, Whitelegge JP, Jones RC, Joshua IG, Thyparambil S, Pantaleon, D, Qiao J, Loo J, Ping P. The murine cardiac 26S proteasome: an organelle awaiting exploration. Ann N Y Acad Sci. 2005;1047:197 – 207.